An efficient reduction protocol for the synthesis of β-hydroxycarbamates from β-nitro alcohols in one pot: a facile synthesis of (-)-β-conhydrine was written by Saikia, Partha Pratim;Baishya, Gakul;Goswami, Abhishek;Barua, Nabin C.. And the article was included in Tetrahedron Letters in 2008.Safety of tert-Butyl (trans-2-hydroxycyclohexyl)carbamate This article mentions the following:
An efficient and practical 1-pot protocol for the reduction of β-nitro alcs. to their corresponding N-(tert-butoxycarbonyl) amino alcs. using Zn-NH4Cl in aqueous MeOH is described. Other reducible groups such as ketones and isolated double bonds remained intact. This methodol. allows a short synthesis of (-)-β-conhydrine to be achieved. In the experiment, the researchers used many compounds, for example, tert-Butyl (trans-2-hydroxycyclohexyl)carbamate (cas: 121282-70-0Safety of tert-Butyl (trans-2-hydroxycyclohexyl)carbamate).
tert-Butyl (trans-2-hydroxycyclohexyl)carbamate (cas: 121282-70-0) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of tert-Butyl (trans-2-hydroxycyclohexyl)carbamate
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts