Potentially tridentate hydrazonic ligands in the synthesis of methyl and acetyl palladium(II) complexes was written by Pelagatti, Paolo;Carcelli, Mauro;Franchi, Francesca;Pelizzi, Corrado;Bacchi, Alessia;Fochi, Andrea;Fruhauf, Hans-Werner;Goubitz, Kees;Vrieze, Kees. And the article was included in European Journal of Inorganic Chemistry in 2000.Quality Control of 6-Methyl-2-pyridinemethanol This article mentions the following:
Potentially tridentate hydrazonic ligands HNNO (HL1-HL5) were used in the synthesis of some Me Pd(II) complexes. Depending on the applied exptl. conditions two different kinds of complexes were obtained. Thus, the reactions between HL1-HL5 and (COD)PdMeCl in Et2O gave bidentate Me complexes Pd(HNN)MeCl (1–5; shown as I; R’/R”/R”’ = H/Me/Me, H/Me/Ph, H/H/Ph, H/Et/Ph, Me/H/Ph), where the ligands maintain a neutral character. However, in the presence of a base such as Et3N or NaOMe, the ligands are deprotonated with the consequent formation of tridentate Me complexes Pd(NNO)Me (7–10; shown as II). In solution, complexes 1–5 tend to lose the hydrazonic proton with elimination of methane and formation of a tridentate chloride complex Pd(NNO)Cl; this tendency can be correlated with the acidity of the free ligands, which was determined On bubbling CO through solutions of 1–5, the corresponding acetyl complexes Pd(HNN)[C(O)Me]Cl (11–15) formed, in which both the cis and trans isomers are present. Their molar ratio is rationalized from the results of a mol. modeling study from electronic considerations. A remarkably different reactivity was found in the carbonylation of the tridentate complexes 7–10; they decompose rapidly and quant. to Pd black and an organic product corresponding to the ligand with an acetyl group bonded to the hydrazonic N. The x-ray structures of a Me complex (3) and its corresponding acetyl (13) derivative were determined In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Quality Control of 6-Methyl-2-pyridinemethanol).
6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Quality Control of 6-Methyl-2-pyridinemethanol
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