Parts-per-million level loading organocatalysed enantioselective silylation of alcohols was written by Park, Sang Yeon;Lee, Ji-Woong;Song, Choong Eui. And the article was included in Nature Communications in 2015.Quality Control of (R)-1-(3-Chlorophenyl)ethanol This article mentions the following:
One p.p.m. loading of a simple 1,1′-bi-2-naphthol-based organocatalyst, I, was enough to achieve highly enantioselective silylation reactions of alcs. RCH(OH)R1 (R = 4-H3CC6H4, 3-F3CC6H4, naphth-1-yl, etc.; R1 = CH3; R = Ph, R1 = HC=CHC6H5). The unprecedented TONs and excellent enantioselectivity are ascribed to the robustness of the catalyst and systematic cooperative hydrogen-bonding organocatalysis in a densely confined chiral space. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Quality Control of (R)-1-(3-Chlorophenyl)ethanol).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Quality Control of (R)-1-(3-Chlorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts