Further ‘tethered’ Ru(II) catalysts for asymmetric transfer hydrogenation (ATH) of ketones; the use of a benzylic linker and a cyclohexyldiamine ligand was written by Martins, Jose E. D.;Morris, David J.;Tripathi, Bhavana;Wills, Martin. And the article was included in Journal of Organometallic Chemistry in 2008.Computed Properties of C8H9ClO This article mentions the following:
The synthesis and characterization of two new Ru(II) catalysts for the asym. transfer hydrogenation (ATH) of ketones is described. In the case of I, the novelty lies in the use of a benzyl tethering group between the asym. ligand part (TsDPEN) and the η6-arene ring, which increases the complex rigidity. For II, the use of a cyclohexyldiamine as a chiral ligand is described for the first time. In the ATH of ketones in formic acid/triethylamine, alcs. with ees of up to 97% were formed. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Computed Properties of C8H9ClO).
(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C8H9ClO
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts