Ruthenium(II) complexes derived from C2-symmetric ferrocene-based chiral bis(phosphinite) ligands: synthesis and catalytic activity towards the asymmetric reduction of acetophenones was written by Ak, B.;Durap, F.;Aydemir, M.;Baysal, A.. And the article was included in Applied Organometallic Chemistry in 2015.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
Chiral secondary alcs. are very important building blocks and valuable synthetic intermediates both in organic synthesis and in the pharmaceutical industry for producing biol. active complex mols. A series of new chiral Ru-phosphinite complexes were prepared from chiral C2-sym. ferrocenyl phosphinites and corresponding chloro complex, [Ru(η6-p-cymene)(μ-Cl)Cl]2. The complexes were characterized using conventional spectroscopic methods. The binuclear complexes were tested as pre-catalysts and were found to be good pre-catalysts for the asym. transfer hydrogenation of substituted acetophenones in basic 2-propanol at 82°C, providing the corresponding optically active alcs. with almost quant. conversion and modest to high enantioselectivities (46-97%). Amongst the all complexes, one complex gave the highest ee of 97% in the reduction of 2-methoxyacetophenone to (S)-1-(2-methoxyphenyl)ethanol at 82°C. Copyright © 2015 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol
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