Syntheses and fungicidal activities of thiazole-5-carboxanilides bearing thioether group was written by Xue, Hansong;Liu, Aiping;Liu, Weidong;Li, Jianming;Ren, Yeguo;Huang, Lu;He, Lian;Ou, Xiaoming;Ye, Jiao;Huang, Mingzhi. And the article was included in Chemical Research in Chinese Universities in 2016.COA of Formula: C4H9NaS This article mentions the following:
A new series of 2-sulfur substituted thiazole carboxanilides I [R1 = Me, Et, t-Bu, etc.; R2 = CF3, CH3; R3 = CF3, OCF3; X = H, Cl, Br] was designed and synthesized via reaction between 2-bromo-thiazole-5-carboxylic acid chlorides and substituted anilines followed by treatment with sodium alkyl thiolates. The title compounds I were screened for their fungicidal activities against Rhizoctonia solani. The fungicidal EC50 of compound I [R1 = Me, R2 = R3 = CF3, X – Cl] against Rhizoctonia solani was 1.28 mg/L, being comparable to that of Thifluzamide. Results indicated that, the most potent compound I [R1 = Me, R2 = R3 = CF3, X – Cl] could be considered as a lead compound for further research. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2COA of Formula: C4H9NaS).
Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.COA of Formula: C4H9NaS
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts