Synthesis of 45S5 Bioglass via a straightforward organic, nitrate-free sol-gel process was written by Rezabeigi, Ehsan;Wood-Adams, Paula M.;Drew, Robin A. L.. And the article was included in Materials Science & Engineering, C: Materials for Biological Applications in 2014.Electric Literature of C6H20CaO11 This article mentions the following:
More than four decades after the discovery of 45S5 Bioglass as the first bioactive material, this composition is still one of the most promising materials in the tissue engineering field. Sol-gel-derived bioactive glasses generally possess improved properties over other bioactive glasses, because of their highly porous microstructure and unique surface chem. which accelerate hydroxyapatite formation. In the current study, a new combination of precursors with lactic acid as the hydrolysis catalyst have been employed to design an organic, nitrate-free sol-gel procedure for synthesizing of 45S5 Bioglass. This straightforward route is able to produce fully amorphous submicron particles of this glass with an appropriately high sp. surface area on the order of ten times higher than that of the melt-derived glasses. These characteristics are expected to lead to rapid hydroxyapatite formation and consequently more efficient bone bonding. In the experiment, the researchers used many compounds, for example, Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5Electric Literature of C6H20CaO11).
Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C6H20CaO11
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts