Tough and Three-Dimensional-Printable Poly(2-methoxyethyl acrylate)-Silica Composite Elastomer with Antiplatelet Adhesion Property was written by Asai, Fumio;Seki, Takahiro;Sugawara-Narutaki, Ayae;Sato, Kazuhide;Odent, Jeremy;Coulembier, Olivier;Raquez, Jean-Marie;Takeoka, Yukikazu. And the article was included in ACS Applied Materials & Interfaces in 2020.SDS of cas: 4074-88-8 This article mentions the following:
Poly(2-methoxyethyl acrylate) (PMEA) has attracted attention as a biocompatible polymer that is used as an antithrombotic coating agent for medical devices, such as during artificial heart and lung fabrication. However, PMEA is a viscous liquid polymer with low Tg, and its phys. strength is poor even if a cross-linker is used, so it is difficult to make tough and freestanding objects from it. Here, we design and fabricate a biocompatible elastomer made of tough, self-supporting PMEA-silica composites. The toughness of the composite elastomer increases as a function of silica particle filling, and its stress at break is improved from 0.3 to 6.7 MPa. The fracture energy of the composite elastomer with 39.5 vol % silica particles is up to 15 times higher than that of the cross-linked PMEA with no silica particles and the material demonstrates stress-strain behavior that is similar to that of biol. soft tissue, which exhibits nonlinear elasticity. In addition, the composite elastomer shows the potential to be an antithrombotic property, while the results of the platelet adhesion test of the composite elastomer show that the number of adhered platelets is not significantly affected by the silica addition As the composite elastomer can be rapidly three-dimensional-printed into complex geometries with high-resolution features, it is expected to contribute to the development of medical devices from readily available materials. In the experiment, the researchers used many compounds, for example, Diethyleneglycoldiacrylate (cas: 4074-88-8SDS of cas: 4074-88-8).
Diethyleneglycoldiacrylate (cas: 4074-88-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.SDS of cas: 4074-88-8
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts