Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism was written by Yu, Qiang;Wang, Fan;Jian, Yating;Chernyshev, Victor M.;Zhang, Yu;Wang, Zhongming;Yuan, Zhenhong;Chen, Xiaoyan. And the article was included in Journal of Molecular Liquids in 2022.Application In Synthesis of 1,2-Propanediol This article mentions the following:
The re-extraction of bioactive compounds from Chinese herb residues is significant for the maximum utilization of biomass resources. However, conventional alc. and aqueous solvents are unsuitable for recovering those compounds In this study, 14 deep eutectic solvents (DESs) were used to improve the efficiency of flavonoid extraction from Glycyrrhiza residues. The maximal total extraction rate (10.68 mg/g) for four flavonoids (liquiritin, isoliquiritin, liquiritigenin, and isoliquiritigenin) was achieved using choline chloride-glycolic acid as the DES under optimal conditions. The extraction rate was 83.03% higher than that by 60% ethanol, a traditional solvent. Anal. of the associated mol. mechanism based on d. functional theory showed that interactions between the solvent and liquiritin were dominated by hydrogen bonds followed by Van der Waals forces, whereas the bonding between the solvent and liquiritigenin only involved Van der Waals forces, thereby verifying the significance of the strength of hydrogen bonding in the DES-flavonoid extraction process. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Application In Synthesis of 1,2-Propanediol).
1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of 1,2-Propanediol
Referemce:
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Alcohols – Chemistry LibreTexts