Enantio sensing property of helicin, the derivative of a natural product: Discrimination of amines and amino alcohols was written by Kumari, Divya;Sachin, S. L.;Suryaprakash, N.. And the article was included in Chemical Physics Letters in 2015.Name: (R)-2-Aminobutan-1-ol This article mentions the following:
The chiral sensing property of helicin (the derivative of natural product obtained by partial oxidation of salicin, extracted from willow tree (Salix helix)) is reported. The use of helicin as a chiral derivatizing agent for the discrimination of amines and amino alcs. is convincingly established using 1H NMR spectroscopy. The large chem. shift separation achieved between the discriminated peaks facilitated the accurate quantification of enantiomeric composition The consistent trend observed in the shifting of imine proton peak (Δδ) of helicin in all the derivatized mols. might aid the determination of spatial configuration. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Name: (R)-2-Aminobutan-1-ol).
(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Name: (R)-2-Aminobutan-1-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts