Paths in the synthesis of 1,9,10-trimethoxy-2,3-methylendioxyaporphine was written by Vinogradova, V. I.;Yunusov, M. S.. And the article was included in Khimiya Prirodnykh Soedinenii in 1985.Safety of Benzo[d][1,3]dioxol-4-ol This article mentions the following:
Treating aldehyde I with NH4OAc-AcOH in refluxing MeNO2 gave 81% nitrostyrene II (R = CH:CHNO2) which was reduced by LiAlH4 in Et2O to give 70% amine II (R = CH2CH2NH2). The latter was treated with (2-bromo-4,5-dimethoxyphenyl)acetic acid to give tetrahydroisoquinoline III via Bischler-Napieralski cyclization, whose attempted photocyclization gave only 2-bromo-4,5-dimethoxybenzaldehyde and unreacted III. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Safety of Benzo[d][1,3]dioxol-4-ol).
Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of Benzo[d][1,3]dioxol-4-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts