The palladium/norbornene-catalyzed ortho-silylmethylation reaction: a practical protocol for ortho-functionalized one-carbon homologation of aryl iodides was written by Sui, Xianwei;Ding, Linlin;Gu, Zhenhua. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Quality Control of Benzo[d][1,3]dioxol-4-ol This article mentions the following:
A palladium/norbornene-catalyzed ortho-silylmethylation reaction using of (iodomethyl)cyclohexyloxydimethylsilane as the electrophile was reported. The ((cyclohexyloxy)dimethylsilyl)methyl group was readily oxidized using the Fleming-Tamao process or by ceric ammonium nitrate to give benzylic alc. derivatives This method was successfully applied in a concise synthesis of a biaryl analog of schisandrins. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Quality Control of Benzo[d][1,3]dioxol-4-ol).
Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Quality Control of Benzo[d][1,3]dioxol-4-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts