Study of 1H NMR based urinary metabolites profiling dataset of canine mammary tumors was written by Lee, Songyeon;Seung, Byung-Joon;Yang, In Seok;Lee, Jueun;Ha, Taewoong;Park, Hee-Myung;Cheong, Jae-Ho;Kim, Sangwoo;Sur, Jung-Hyang;Hwang, Geum-Sook;Nam, Hojung. And the article was included in Scientific Data in 2022.Formula: C3H8O2 This article mentions the following:
The identification of efficient and sensitive biomarkers for non-invasive tests is one of the major challenges in cancer diagnosis. To address this challenge, metabolomics is widely applied for identifying biomarkers that detect abnormal changes in cancer patients. Canine mammary tumors exhibit physiol. characteristics identical to those in human breast cancer and serve as a useful animal model to conduct breast cancer research. Here, we aimed to provide a reliable large-scale metabolite dataset collected from dogs with mammary tumors, using proton NMR spectroscopy. We identified 55 metabolites in urine samples from 20 benign, 87 malignant, and 49 healthy control subjects. This dataset provides details of mammary tumor-specific metabolites in dogs and insights into cancer-specific metabolic alterations that share similar mol. characteristics. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Formula: C3H8O2).
1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Formula: C3H8O2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts