Development of an enolate alkynylation approach towards the synthesis of the taiwanschirin natural products was written by Haughey, Maxwell B.;Christensen, Kirsten E.;Poole, Darren L.;Donohoe, Timothy J.. And the article was included in Chemical Science in 2021.Safety of Benzo[d][1,3]dioxol-4-ol This article mentions the following:
Through the use of model studies, an approach was conceived towards the synthesis of the taiwanschirin family of natural products. These are structurally complex compounds which represent highly challenging and biol. active targets for total synthesis. This work described a successful synthesis of the complex taiwanschirin fused [8,6,5] core through a novel alkynylation reaction coupled with an intramol. Heck reaction used to construct the 8-membered ring. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2Safety of Benzo[d][1,3]dioxol-4-ol).
Benzo[d][1,3]dioxol-4-ol (cas: 69393-72-2) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Safety of Benzo[d][1,3]dioxol-4-ol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts