Regioselective hydroboration-oxidation and -amination of fluoro-substituted styrenes was written by Ramachandran, P. Veeraraghavan;Madhi, Sateesh;O’Donnell, Martin J.. And the article was included in Journal of Fluorine Chemistry in 2006.Synthetic Route of C9H9F3O This article mentions the following:
Hydroboration of fluorinated styrenes with common hydroborating agents results in polymerization However, regioselective hydroboration has been achieved by utilizing iodoborane-dimethyl sulfide. A series of fluorinated β-phenethyl alcs. and amines, e.g., I [R = OH, NH2] were synthesized via this methodol. In the experiment, the researchers used many compounds, for example, 2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6Synthetic Route of C9H9F3O).
2-(4-(Trifluoromethyl)phenyl)ethanol (cas: 2968-93-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Synthetic Route of C9H9F3O
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts