Scandium triflate as an efficient and useful catalyst for the synthesis of β-amino alcohols by regioselective ring opening of epoxides with amines under solvent-free conditions was written by Placzek, Andrew T.;Donelson, James L.;Trivedi, Rushi;Gibbs, Richard A.;De, Surya K.. And the article was included in Tetrahedron Letters in 2005.Name: Trans-2-(benzylamino)cyclohexanol This article mentions the following:
A simple and efficient method was developed for the synthesis of β-amino alcs. by ring opening of epoxides in the presence of a catalytic amount of Sc(O3SCF3)3 at room temperature under solvent-free conditions. The reaction works well with both aromatic and aliphatic amines. High regio- and diastereoselectivity can be considered as a noteworthy advantage of this method. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6Name: Trans-2-(benzylamino)cyclohexanol).
Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: Trans-2-(benzylamino)cyclohexanol
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Alcohols – Chemistry LibreTexts