Cyanobacterium-catalyzed asymmetric reduction of ketones was written by Nakamura, K.;Yamanaka, R.;Tohi, K.;Hamada, H.. And the article was included in Tetrahedron Letters in 2000.Safety of (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
Synechococcus sp. PCC 7942, a cyanobacterium, acted as a biocatalyst to reduce aryl Me ketones into the corresponding (S)-alcs. with excellent enantioselectivities under illumination. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Safety of (S)-1-(2-Fluorophenyl)ethanol).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Safety of (S)-1-(2-Fluorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts