Zhong, Wen-qu published the artcileComparison of efficacy of hemabate and oxytocin in prevention of high-risk cesarean section postpartum hemorrhage, COA of Formula: C25H47NO8, the publication is Xiandai Zhenduan Yu Zhiliao (2014), 25(19), 4421-4422, database is CAplus.
82 Cases of patients with high-risk cesarean section postpartum hemorrhage were divided into observation group and control group, 41 cases in each group. The observation group received i.m. injection of hemabate, and the control group received i.m. injection of oxytocin after cesarean section. The amount of bleeding 2 h after surgery, amount of bleeding 2 h after surgery and bleeding rate of observation group were 212.6 ± 57.8 mL, 298.6 ± 71.4 mL and 17.1%, and those of control group were 358.7 ± 62.5 mL, 459.7 ± 86.3ml and 41.5%. The incidence of adverse reactions of observation group was 4.88%, and that of control group was 19.51%. The differences of all the data between groups were statistically significant (P < 0.05 or P < 0.01). Compared with traditional drugs, hemabate can effectively control bleeding amount and bleeding rate in preventing high-risk cesarean section postpartum hemorrhage, has high drug safety and is recommended to be used in clinic.
Xiandai Zhenduan Yu Zhiliao published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C10H15NO, COA of Formula: C25H47NO8.
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