Sherwood, Alexander M. published the artcileModular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands, SDS of cas: 57044-25-4, the publication is Organic Letters (2017), 19(19), 5414-5417, database is CAplus and MEDLINE.
Informed by previous semisynthetic work on salvinorin A, a modular total synthesis has been developed capable of producing novel compounds targeting the κ-opioid receptor. The strategy has permitted the deliberate simplification and introduction of functionality about the target mol. to provide access to mol. features on salvinorin A otherwise unattainable by semisynthesis. Using this approach, a potent pseudo-neoclerodane κ-opioid receptor ligand (I) has been realized.
Organic Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C8H5F3N4, SDS of cas: 57044-25-4.
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