Chinese Chemical Letters published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Quality Control of 101-98-4.
Nie, Ai Hua published the artcileDrug discovery based on the structure of FKBPs: design, synthesis and evaluation of L-1,4-thiazane-3-carboxylic acid derivatives as neuroimmunophilin ligands, Quality Control of 101-98-4, the publication is Chinese Chemical Letters (2005), 16(2), 163-166, database is CAplus.
Based on the structure of FK506, FKBP12 and calcineurin complex and the interactive characteristics of small mol. ligands with FK-506-binding proteins (FKBPs), a series of L-tetrahydro-1,4-thiazine-3-carboxylic acid derivatives I [X = O, R = PhCH2NMeCH2CH2, PhCH:CHCH2, 3-cyclohexylpropyl, 4-O2NC6H4CH2, etc.; X = NH, R = Me2CHCH2CH(CO2Et), PhCH2CH(CO2CH2Ph), etc.] was designed and synthesized as neuroimmunophilin ligands. The results of evaluation show that I [X = O; R = (PhCH2OCH2)2CH] (N308) has a great promise as a candidate of neuroprotective and neuroregenerative agent.
Chinese Chemical Letters published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C10H15NO, Quality Control of 101-98-4.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts