Martin-Montero, Raul published the artcileNi-catalyzed Reductive Deaminative Arylation at sp3 Carbon Centers, Quality Control of 96-20-8, the publication is Organic Letters (2019), 21(8), 2947-2951, database is CAplus and MEDLINE.
A Ni-catalyzed reductive deaminative arylation at unactivated sp3 carbon centers is described. This operationally simple and user-friendly protocol exhibits excellent chemoselectivity profile and broad substrate scope, thus complementing existing metal-catalyzed cross-coupling reactions to forge sp3 C-C linkages. These virtues have been assessed in the context of late-stage functionalization, hence providing a strategic advantage to reliably generate structure diversity with amine-containing drugs.
Organic Letters published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Quality Control of 96-20-8.
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