Lu, Li-ping published the artcileHemabate combined with sodium potassium magnesium calcium and glucose injection in high-risk cesarean section, Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Shequ Yixue Zazhi (2012), 10(24), 33-34, database is CAplus.
Objective: To discuss the application of Hemabate combined with Na-K-Mg-Ca-glucose injection to high-risk cesarean section. Methods: 80 women with indication of high-risk cesarean section were divided into a Hemabate combined with Na-K-Mg-Ca-glucose injection group (group A) and a Hemabate combined with Ringer’s lactate injection group (group B). The blood pressure, HR, PaO2, hemorrhage, Hemabate dose, and side effect ratio were monitored. Results: Hemabate dose of Group A was 250 μg 32 cases, 500 μg 6 cases, and 750 μg 2 cases, and that of Group B was 250 μg 22 cases, 500 μg 12 cases, and 750 μg 6 cases with statistical significance (P < 0.05). Group B had high hemorrhage than Group A 2 h postoperatively and 24 h postoperatively with statistical significance (all P < 0.05). Group A had postoperative hemorrhage > 500 mL 8 cases (20%), uterine filling and surgery 3 cases (7.5%) and nausea and vomiting 17 cases (42.5%). Group B had postoperative hemorrhage 500 mL 17 cases (42.5%), uterine filling and surgery 6 cases (15), and nausea and vomiting 32 cases (80%) with statistical significance (all P < 0.05). Conclusion: The Hemabate combined with perioperative i.v. infusion of Na-K-Mg-Ca-glucose injection for high-risk cesarean section could reduce hemorrhage, Hemabate dose, and nausea and vomiting.
Shequ Yixue Zazhi published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts