Liu, Miao published the artcileClinical research of carboprost tromethamine for preventing and treating postpartum hemorrhage of high risk puerpera undergoing cesarean, HPLC of Formula: 58551-69-2, the publication is Xiandai Zhongxiyi Jiehe Zazhi (2013), 22(2), 144-145, 205, database is CAplus.
The objective was to observe the effect and security of carboprost tromethamine for preventing and treating postpartum hemorrhage of high risk puerpera undergoing cesarean. The method includes dividing 397 puerpera undergoing cesarean with high risk of postpartum hemorrhage into 3 groups: oxytocin group (injection of 20 IU oxytocin into hyster and i.v. infusion of 20 IU oxytocin, n=131), oxytocin+carboprost tromethamine group (injection of 20 IU oxytocin 20 IU+carboprost tromethamine 250μg into hyster, n=152), and carboprost tromethamine group (injection of carboprost tromethamine 250μg into hyster, n=114), calculating bleeding amount during the cesarean and 2 h after cesarean and the total bleeding amount, and observing the untoward effects. The results show that carboprost tromethamine can significantly reduce the bleeding amount during the cesarean and after cesarean, and the combination of carboprost tromethamine and oxytocin has better effect, and the untoward effect is little.
Xiandai Zhongxiyi Jiehe Zazhi published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, HPLC of Formula: 58551-69-2.
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