Liao, Liangkun published the artcileAnti-inflammatory effect of essential oil from Amomum Tsaoko Crevost et Lemarie, Quality Control of 106-25-2, the publication is Journal of Functional Foods (2022), 105087, database is CAplus.
Amomum Tsaoko Crevost et Lemarie is a kind of spices and traditional Chinese medicines with great com. value. Traditional treatment often uses essential oils from Amomum Tsaoko in aromatherapy. In this study, researchers analyzed the composition of steam-distilled essential oil from Amomum tsaoko (ATEO) and evaluated its potential antioxidant and anti-inflammatory activity. GC-MS identified a total of 33 volatile compounds, the majority of which were alc. (1,8-cineole and nerol) and aldehyde ((2E)-2-decenal) compounds Addnl., ATEO showed great anti-inflammatory activity in LPS-induced RAW 264.7 macrophages. ATEO markedly inhibited the nitric oxide (NO) release, and decreased the expression level of TNF-α, IL-1β, IL-6 and monocyte chemotactic protein-1 (MCP-1) in a dose-dependent manner. Furthermore, ATEO significantly reduced the expression of iNOS, COX-2, NF-κB p-p65 and p-ERK. These results suggested that ATEO has great anti-inflammatory activity in LPS-induced RAW 264.7 cells, which will facilitate the development of ATEO as a functional food.
Journal of Functional Foods published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Quality Control of 106-25-2.
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