Kang, Iou-Jiun’s team published research in Bioorganic & Medicinal Chemistry Letters in 19 | CAS: 23351-09-9

Bioorganic & Medicinal Chemistry Letters published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Formula: C10H9NO.

Kang, Iou-Jiun published the artcileDesign, synthesis, and anti-HCV activity of thiourea compounds, Formula: C10H9NO, the publication is Bioorganic & Medicinal Chemistry Letters (2009), 19(7), 1950-1955, database is CAplus and MEDLINE.

A series of thiourea derivatives, e.g., I, were synthesized and their antiviral activity was evaluated in a cell-based HCV subgenomic replicon assay. SAR studies revealed that the chain length and the position of the alkyl linker largely influenced the in vitro anti-HCV activity of this class of potent antiviral agents. Among this series of synthesized compounds, the thiourea derivative with a six-carbon alkyl linker at the meta-position of the central Ph ring was identified as the most potent anti-HCV inhibitor (EC50 = 0.047 μM) with a selectivity index of 596.

Bioorganic & Medicinal Chemistry Letters published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Formula: C10H9NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts