Chadeayne, Andrew R.’s team published research in Inorganic Chemistry in 43 | CAS: 17877-23-5

Inorganic Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Name: Triisopropylsilanol.

Chadeayne, Andrew R. published the artcileThe Course of (R2R’SiO)3TaCl2 (R = tBu, R’ = H, Me, Ph, tBu (silox); R = iPr, R’ = tBu, iPr) Reduction Is Dependent on Siloxide Size, Name: Triisopropylsilanol, the publication is Inorganic Chemistry (2004), 43(11), 3421-3432, database is CAplus and MEDLINE.

Various sized siloxides (Cy3SiO > tBu3SiO > tBu2PhSiO > tBu2MeSiO approx. iPr2tBuSiO > iPr3SiO > tBu2HSiO) were used to make (R2R’SiO)3TaCl2 (R = tBu, R’ = H (1-H), Me (1-Me), Ph (1-Ph), 1–tBu (1); R = iPr, R’ = tBu (1–iPr2); R = R’ = iPr (1–iPr3); R = R’ = cyclohexyl). Product analyses of Na amalgam reductions of several dichlorides suggest that [(R2R’SiO)3Ta]2(μ-Cl)2 may be a common intermediate. When the siloxide is large (1–tBu), formation of the Ta(III) species (tBu3SiO)3Ta (6) occurs via disproportionation. When the siloxide is small, the Ta(IV) intermediate is stable (e.g., [(iPr3SiO)3Ta]2(μ-Cl)2 (2)), and when intermediate sized siloxides were used, solvent bond activation via unstable Ta(III) tris-siloxides probably occurs. Under H, reductions of 1-Me and 1-Ph provide Ta(IV) and Ta(V) hydrides [(tBu2MeSiO)3Ta]2(μ-H)2 (4-Me) and (tBu2PhSiO)3TaH2 (7-Ph), resp.

Inorganic Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Name: Triisopropylsilanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts