Peng, Ke’s team published research in Soft Matter in 2019 | CAS: 111-87-5

Soft Matter published new progress about Gelation agents. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Peng, Ke published the artcileGelled non-toxic microemulsions: phase behavior & rheology, Category: alcohols-buliding-blocks, the main research area is gelled non toxic microemulsion phase diagram rheol.

Bicontinuous microemulsions gelled with a low mol. weight gelator have been shown to be an orthogonally self-assembled system. With the mech. stability provided by the gel network, gelled non-toxic bicontinuous microemulsions have the potential to be an efficient transdermal drug delivery carrier. However, up to now no suitable system has been formulated for transdermal drug delivery. To fill this gap, we formulated and characterized a gelled non-toxic bicontinuous microemulsion suitable for the mentioned application. Starting from a previously studied scouting system, namely, H2O-n-octane-n-octyl β-D-glucopyranoside (β-C8G1)-1-octanol, the co-surfactant and the oil were replaced by non-toxic components. Subsequently, the expensive pure surfactant was replaced by cheap tech.-grade surfactants (Plantacare series) to make the system economical. Having formulated the non-toxic microemulsion H2O-IPM-Plantacare 1200 UP-1,2-octanediol, three low mol. weight gelators were studied with regard to the gelation of both the scouting system and the non-toxic system. The chosen gelators were 12-hydroxyoctadecanoic acid (12-HOA), 1,3:2,4-dibenzylidene-D-sorbitol (DBS), and N,N’-dibenzoyl-L-cystine (DBC). We found that only DBS gels the non-toxic microemulsion. The gelled non-toxic bicontinuous microemulsion H2O-IPM-Plantacare 1200 UP-1,2-octanediol was characterized with oscillatory shear rheometry and small-angle neutron scattering (SANS) at a DBS concentration of 0.3 wt% to verify that the system is indeed a gel and that the microstructure of the microemulsion is not altered by the gel network.

Soft Matter published new progress about Gelation agents. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts