Pan, Lei published the artcileTransition-Metal-Free Photoredox Phosphonation of Aryl C-N and C-X Bonds in Aqueous Solvent Mixtures, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, the main research area is aryl halide photoredox cross coupling reaction phosphite phenothiazine catalyst; aromatic aryl phosphonate preparation green solvent.
Herein, the authors present an efficient and mild methodol. for the synthesis of aromatic phosphonate esters in good to excellent yields using 10H-phenothiazine, an inexpensive commodity chem., as a photoredox catalyst. The reaction exhibits wide functional group compatibility enabling the transformation in the presence of ketone, amide, ester, amine, and alc. moieties. Importantly, the reaction proceeds using a green solvent mixture primarily composed of H2O, thus lowering the environmental footprint of this transformation compared to current methods. The transformation also proceeds under atm. conditions, which further differentiates it from current methods that require inert atm. Mechanistic work using fluorescence quenching experiments and radical trapping approaches support the proposed mechanism.
ACS Sustainable Chemistry & Engineering published new progress about Green solvents. 124-76-5 belongs to class alcohols-buliding-blocks, name is rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol, and the molecular formula is C10H18O, Application of rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol.
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Alcohols – Chemistry LibreTexts