Wang, Chunfang published the artcileTo explore the best time of hemabate in prevention and treatment of postpartum hemorrhage, Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Hebei Yixue (2017), 23(1), 52-54, database is CAplus.
Objective: To study the best time of hemabate in prevention and treatment of postpartum hemorrhage, to provide basis for clin. diagnosis and treatment. Methods: 114 cases of cesarean section with bleeding tendency from Feb. 2014 to Feb. 2016 in our hospital were selected, the patients were randomly divided into group I, group II and group III, 38 cases in each group, group I injection of oxytocin and hemabate immediately after fetal delivery, group II injection of the oxytocin immediately after fetal delivery, application of hemabate when uterine atony, group III injection of oxytocin immediately after fetal delivery, not using hemabate, the bleeding intraoperative, back to the ward to postoperative 2H and 2H to postpartum 24 h were compared between the three groups. Results: The bleeding during operation of group I significantly lower than II group and III group (P<0.05), there were no significant amount of intraoperative blood loss in group II and group III (P>0.05); back to the ward to postoperative 2H bleeding of group I and group II were significantly lower than those in the group III (P<0.05), group I and group II were not statistically significant (P>0.05), 2H to postpartum 24h bleeding of group I and group II were significantly lower than those in the group III (P<0.05), group I and group II were not statistically significant (P>0.05). Conclusion: Fetal delivery immediately injection of oxytocin and hemabate could effectively reduce the amount of postpartum hemorrhage, it is the best time to prevent postpartum hemorrhage.
Hebei Yixue published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C8H11BO2, Safety of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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