Sasikumar, M.’s team published research in Synthetic Communications in 42 | CAS: 156453-53-1

Synthetic Communications published new progress about 156453-53-1. 156453-53-1 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Benzene,Naphthalene,Alcohol,Ether, name is (R)-3-(Naphthalen-1-yloxy)-1-phenylpropan-1-ol, and the molecular formula is C19H18O2, Related Products of alcohols-buliding-blocks.

Sasikumar, M. published the artcileSimple and efficient synthesis of (S)-dapoxetine, Related Products of alcohols-buliding-blocks, the publication is Synthetic Communications (2012), 42(20), 3061-3067, database is CAplus.

A refinement in the synthetic strategy for (S)-dapoxetine was described. The key features of synthetic strategy include (a) a Sharpless asym. epoxidation and regioselective reductive ring opening of a 2,3-epoxy alc. to elaborate the hydroxy-bearing stereogenic center at the benzylic position; (b) regioselective functionalization of the 1-naphthol and the amine functionality through Mitsunobu procedures; and (c) Eschweiler-Clarke reductive methylation to access the target mol.

Synthetic Communications published new progress about 156453-53-1. 156453-53-1 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Benzene,Naphthalene,Alcohol,Ether, name is (R)-3-(Naphthalen-1-yloxy)-1-phenylpropan-1-ol, and the molecular formula is C19H18O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts