Prasad, Durga’s team published research in RSC Advances in 10 | CAS: 96-20-8

RSC Advances published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, SDS of cas: 96-20-8.

Prasad, Durga published the artcileR-VAPOL-phosphoric acid based 1H and 13C-NMR for sensing of chiral amines and acids, SDS of cas: 96-20-8, the publication is RSC Advances (2020), 10(4), 2303-2312, database is CAplus and MEDLINE.

Enantiomers have significant importance in pharmaceuticals, biol. and modern chem. and therefore distinguishing and quantifying the enantiomeric forms is of utmost importance. Herein, we propose diphenyl-3,3′-biphenanthryl-4,4′-diyl phosphate (R-VAPOL-PA) as a promising chiral solvating agent to discriminate amines and acids of poly-functional groups such as chiral amines, amino alcs. and hydroxy acids. The methodol. approach involves using the nature of hydrogen bonds and ion pairs as a mode of weak interactions to form diastereomers where the probe is associated with enantiomers. The resulting diastereomer difference in the NMR spectrum enables the chiral discrimination with a complete baseline peak separation and an accurate enantiomeric excess (ee) anal. We also carried out d. functional theory (DFT) calculations to understand the complex formation to explain enantiodiscrimination by analyzing the formation and stability of different chiral complexes. The binding energy differences between enantiomeric forms revealed by DFT calculations are qual. in agreement with the diastereomer difference in the NMR spectrum and unequivocally establishes the suggested exptl. protocol of R-VAPOL-PA-based enantiomeric discrimination.

RSC Advances published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, SDS of cas: 96-20-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts