Ishidate, Motoi Jr.’s team published research in Mutation Research, Genetic Toxicology Testing in 48 | CAS: 4543-95-7

Mutation Research, Genetic Toxicology Testing published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, Formula: C8H19NO.

Ishidate, Motoi Jr. published the artcileChromosome tests with 134 compounds on Chinese hamster cells in vitro – a screening for chemical carcinogens, Formula: C8H19NO, the publication is Mutation Research, Genetic Toxicology Testing (1977), 48(3-4), 337-53, database is CAplus.

Chromosomal aberration tests in vitro were carried out on Chinese hamster cells grown in culture with various chems., including carcinogenic N-nitroso compounds and their related derivatives, food additives, medical drugs, pesticides and other chems. commonly used in laboratories or industries. Of the 134 chems. tested, 63 gave neg. results in the test system even with doses at which the cell growth was markedly inhibited. Nearly all compounds known to be mutagenic in bacteria were also pos. in this system. Both urethane [51-79-6] and diethylstilbestrol [56-53-1] were pos., even though they are known to be carcinoenic but not mutagenic in bacteria. Compounds such as N-alkyl-N’-nitrogunidines, barbital [57-44-3], Na benzoate [532-32-1], saccharin sodium [128-44-9], NaNO2, NaNO3, and 4-aminoquinoline-1-oxide [2508-86-3] were pos. in the chromosome tests, but they have not been conclusively tested for their carcinogenicity.

Mutation Research, Genetic Toxicology Testing published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, Formula: C8H19NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts