Ghavtadze, Nugzar published the artcileConversion of 1-alkenes into 1,4-diols through an auxiliary-mediated formal homoallylic C-H oxidation, Synthetic Route of 17877-23-5, the publication is Nature Chemistry (2014), 6(2), 122-125, database is CAplus and MEDLINE.
The ubiquitous nature of C-H bonds in organic mols. makes them attractive as a target for rapid complexity generation, but brings with it the problem of achieving selective reactions. In developing new methodologies for C-H functionalization, alkenes are an attractive starting material because of their abundance and low cost. Here we describe the conversion of 1-alkenes into 1,4-diols. The method involves the installation of a new Si,N-type chelating auxiliary group on the alkene followed by iridium-catalyzed C-H silylation of an unactivated δ-C(sp3)-H bond to produce a siloxane intermediate. Oxidation of the C-Si bonds affords a 1,4-diol. The method is demonstrated to have broad scope and good functional group compatibility by application to the selective 1,4-oxygenation of several natural products and derivatives
Nature Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, Synthetic Route of 17877-23-5.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts