Yang, Cai-hong published the artcileAnalysis of clinical efficacy and safety of carboprost tromethamine combined with Barkri balloon in treatment of postpartum hemorrhage, Application In Synthesis of 58551-69-2, the publication is Xiandai Zhenduan Yu Zhiliao (2017), 28(16), 3003-3005, database is CAplus.
To explore the clin. efficacy and safety of carboprost tromethamine combined with Barkri balloon in the treatment of postpartum hemorrhage. A total of 90 patients with postpartum hemorrhage admitted to our hospital from Jan. 2015 to Dec. 2016 were selected and randomly divided into a control group and an observation group with 45 cases each. In the control group, a Bakri balloon was injected from the vagina or uterine incision during cesarean section, and 300mL of normal saline was injected. Patients in the observation group were injected with carboprost tromethamine for combination therapy on the basis of the control group. Both groups of patients were treated for 24 h. The clin. efficacy of the two groups of patients was compared, systolic blood pressure (SBP), diastolic blood pressure (DBP) and blood oxygen saturation (SaO2), blood loss and adverse reactions were compared for safety evaluation of the combination. Results: After treatment, the total effective rates of the observation group and the control group were 93.33% and 80.00%, resp., and there was a statistical difference between the two groups (P < 0.05). There was no statistical difference in the amount of bleeding before treatment between the two groups of patients with postpartum hemorrhage (P > 0.05). After 2h and 24h of hemostatic treatment, the bleeding volume of the observation group was significantly less than that of the control group (P < 0.05). There was no significant difference in SBP, DBP and SaO2 between the two groups of patients with postpartum hemorrhage before and after treatment (P > 0.05). There was no significant difference in the occurrence of adverse reactions between the two groups (P > 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups. Carprost tromethamine combined with Bakri balloon has good clin. efficacy and high safety in the treatment of postpartum hemorrhage, and it is worthy of clin. application.
Xiandai Zhenduan Yu Zhiliao published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C26H41N5O7S, Application In Synthesis of 58551-69-2.
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