Wang, Hui-min published the artcileClinical analysis of carbetocin combined with romethamine for preventing high-risk postpartum hemorrhage after caesarean section, Synthetic Route of 58551-69-2, the publication is Xiandai Zhongxiyi Jiehe Zazhi (2013), 22(26), 2916-2917, database is CAplus.
This paper aims to explore the clin. anal. of carbetocin combined with romethamine for preventing high-risk postpartum hemorrhage after caesarean section. 76 Cases of high-risk factor caesarean section puerpera were divided into control group and treatment group(n=38). In control group, the puerpera were injected with oxytocin 20 IU right after delivery, and i.v. infused with carbetocin 100 μg. Based on the treatment of control group, the treatment group was injected with romethamine 250 μg. The hemorrhage amount, side effect of drug and exhaust time in both groups were observed during operation, 2 h and 24 h after operation. The hemorrhage amounts during operation, 2 h and 24 h after operation in treatment group were significantly less than those of control group(all P<0.05). The exhaust time of treatment group was shorten than that of control group(P<0.05). There were no significant differences in drug side effects between two groups. Carbetocin combined with romethamine has definite effect and less side effect for preventing high-risk postpartum hemorrhage after caesarean section.
Xiandai Zhongxiyi Jiehe Zazhi published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C8H13ClN2O, Synthetic Route of 58551-69-2.
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