Sun, Ying-Jie’s team published research in Chemical Communications (Cambridge, United Kingdom) in 56 | CAS: 25240-59-9

Chemical Communications (Cambridge, United Kingdom) published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C18H17N5O3, Recommanded Product: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol.

Sun, Ying-Jie published the artcileRegioselective synthesis and anticancer evaluation of H2O2-activable nucleosides, Recommanded Product: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(48), 6484-6487, database is CAplus and MEDLINE.

We describe here the design, synthesis, and biol. evaluation of H2O2-activatable dioxaboronalyl nucleosides via an efficient and regioselective functionalization of unprotected precursors. Biol. evaluation of a H2O2-specific responsive prodrug of gemecitabin demonstrates an extremely fast activation, low toxicity and enhanced anticancer effects in two cell lines.

Chemical Communications (Cambridge, United Kingdom) published new progress about 25240-59-9. 25240-59-9 belongs to alcohols-buliding-blocks, auxiliary class Boronic acid and ester,Boronic Acids,Boronate Esters, name is 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol, and the molecular formula is C18H17N5O3, Recommanded Product: 4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts