Ma, Xinxia published the artcileObservation on carboprost tromethamine and oxytocin for reduction of hemorrhage in caesarean section, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, the publication is Zhonghua Fuyou Linchuang Yixue Zazhi, Dianziban (2014), 10(5), 73-76, database is CAplus.
Objective: To observe the effect of carboprost tromethamine (hemabate) and oxytocin in cesarean section for preventing and reducing the intraoperative bleeding and compare their adverse reaction. Methods: From Nov. 2013 to March 2014, a total of 40 parturient women underwent cesarean section were included in the study. They were randomly divided into group I (20 cases using carboprost tromethamine injection) and group II (20 cases using oxytocin) according to different drugs for the injection into their uterine corpus immediately after fetal disengagement. There were no significant differences in maternal age, gestational age, body weight in general between two groups (P > 0.05). The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Shanghai First Maternity and Infant Hospital. Informed consent was obtained from each participants. Results: The amount of blood loss during cesarean section in group I was obviously lower than that of group II (P < 0.05). There were significant differences in vital signs at 10 min after treatment between two groups (P < 0.05). The incidence rate of adverse reaction in group I was significantly higher than that of group II (P < 0.01). Conclusion: Carboprost tromethamine injection in caesarean operation can effectively decrease the intraoperative bleeding, but more attention should be paid on its adverse reaction.
Zhonghua Fuyou Linchuang Yixue Zazhi, Dianziban published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Application of 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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