Lu, Jian-ping’s team published research in Zhongguo Fuyou Baojian in 31 | CAS: 58551-69-2

Zhongguo Fuyou Baojian published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Category: alcohols-buliding-blocks.

Lu, Jian-ping published the artcileClinical effect of hemabate in prevention and treatment of postpartum hemorrhage and adverse events among high risk pregnant women receiving cesarean section, Category: alcohols-buliding-blocks, the publication is Zhongguo Fuyou Baojian (2016), 31(18), 3717-3719, database is CAplus.

Objective To explore the clin. effect of hemabate in prevention and treatment of postpartum hemorrhage and adverse events among high risk pregnant women receiving cesarean section, accumulate experience for clin. optimization strategy among the population. Methods From June 2010 to Oct. 2013, 78 pregnant women underwent cesarean section in Department of Obstetrics and Gynecol. in the hospital were selected, then they were divided into study group and control group according to random number table, 39 cases in each group. The cases in control group were treated by oxytocin combined with carboprost methylate suppositories, while the cases in study group were treated by hemabate. The amounts of blood loss and urine volumes during operation and at 2 and 24 h after operation in the two groups were recorded, the incidence rates of adverse events in the two groups were compared. Results The amount of blood loss during operation and at 2 and 24 h after operation in study group were statistically significantly lower than those in control group (P<0.05). Urine volumes during operation and at 2 and 24 h after operation in study group were statistically significantly higher than those in control group (P<0.05). The incidence rate of adverse reactions in study group was statistically significantly lower than that in control group (P<0.05). Conclusion For the high-risk pregnant women receiving cesarean section, the clin. efficacy and safety of hemabate in prevention and treatment of postpartum hemorrhage are better than those of oxytocin combined with carboprost methylate suppositories, which is worthy of further promotion and application in clin. practice.

Zhongguo Fuyou Baojian published new progress about 58551-69-2. 58551-69-2 belongs to alcohols-buliding-blocks, auxiliary class Chiral,Alkenyl,Amine,Aliphatic cyclic hydrocarbon,Ester,Alcohol,Inhibitor,, name is 2-Amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)cyclopentyl)hept-5-enoic acid, and the molecular formula is C25H47NO8, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts