Sun, Shuzhou published the artcileDetermination of 26 chemical drugs for the treatment of cough and asthma added illegally in herbal tea by high performance liquid chromatography-tandem mass spectrometry, Quality Control of 23828-92-4, the publication is Jinri Yaoxue (2021), 31(3), 195-199, database is CAplus.
OBJECTIVE To establish a rapid screening method for determination of 26 chem. drugs for the treatment of cough and asthma added illegally in herbal tea. METHODS This method involved liquid chromatog.-tandem mass spectrometry. The samples were extracted with methanol, filtrated by 0.22 μm microporous filters and finally separated on a C18 column (2.1 mm×150 mm, 3.5 μm) by using acetonitrile and water (containing 5 mmol·L-1 ammonium formate and 0.1% formic acid) as mobile phase. Qual. and quant. anal. were carried out in multiple reaction monitoring (MRM) model. RESULTS The correlative coefficient of 26 chem. drugs were above 0.995. The average recoveries were 61.2% ∼ 115.6%, the relative standard deviations ranged from 1.0% to 2.0% (n=6). CONCLUSION The method is simple, rapid and sensitive. It is suitable for the determination of 26 chem. drugs for the treatment of cough and asthma added illegally in herbal tea.
Jinri Yaoxue published new progress about 23828-92-4. 23828-92-4 belongs to alcohols-buliding-blocks, auxiliary class Membrane Transporter/Ion Channel,Sodium Channel, name is trans-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride, and the molecular formula is C12H15ClO3, Quality Control of 23828-92-4.
Referemce:
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