Qiu, Jiaqi published the artcileRecyclable DMAP-Functionalized polymeric nanoreactors for highly efficient acylation of alcohols in aqueous systems, Synthetic Route of 584-02-1, the main research area is DMAP functionalize block copolymer preparation thermal stability; alc anhydride heterogeneous catalyst acylation green chem; ester preparation.
In this study, small-mol. catalysts 4-(N,N-dimethylamino)pyridine (DMAP) functionalized nanoreactors were constructed by self-assembly of amphiphilic block copolymers with DMAP moieties in the hydrophobic block, leading to heterogeneous catalysts with excellent dispersity in water. The key preparation route included reversible addition-fragmentation chain transfer (RAFT) polymerization of 2-(N-methyl-N-(4-pyridyl)amino)ethyl methacrylate (MAPMA) and Me methacrylate (MMA) using poly (oligomeric (ethylene glycol) Me ether methacrylate) (POEGMA) as a hydrophilic macromol. RAFT reagent. The characterization by dynamic light scattering (DLS) and transmission electron microscopy (TEM) shows that the nanoreactors possess a core-shell nanostructure with the diameter of around 110 nm. The resulting polymeric nanoreactors showed excellent catalytic activity for acylation of alcs. in water. High conversion of a variety of alc. (>99%) and excellent product selectivity were achieved. The high catalytic efficiency of the nanoreactors may be attributed to the enhancement of the interaction between the reactant and the catalyst in the confined hydrophobic space, which simulates how enzymes usually work. Moreover, the catalyst was easily recovered by thermoresponsive separation and reused with high activity for more than 5 cycles. This study presents an efficient approach to achieve green catalytic reactions which were normally incompatible to aqueous conditions, potentially applicable to other catalytic systems such as metal-mediated organic transformations.
Polymer published new progress about Acylation. 584-02-1 belongs to class alcohols-buliding-blocks, name is 3-Pentanol, and the molecular formula is C5H12O, Synthetic Route of 584-02-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts