Ishikawa, Nobuo’s team published research in Journal of Fluorine Chemistry in 24 | CAS: 83706-94-9

Journal of Fluorine Chemistry published new progress about 83706-94-9. 83706-94-9 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is (E)-4,4,4-Trifluorobut-2-en-1-ol, and the molecular formula is C4H5F3O, Application In Synthesis of 83706-94-9.

Ishikawa, Nobuo published the artcilePreparation of trifluoromethylated allylic alcohols from trifluoroacetaldehyde and organometallic compounds, Application In Synthesis of 83706-94-9, the publication is Journal of Fluorine Chemistry (1984), 24(4), 419-30, database is CAplus.

A number of allylic alcs. bearing a CF3 group at the α- or γ-position, and α-trifluoromethylated γ-enols and -ynols were prepared by the reaction of CF3CHO with a variety of organometallic compounds Most of the Reformatskii- or Grignard-type reactions required promotion by ultrasound. E.g., Reformatskii-type reaction of CF3CHO and BrCH2CO2Et in the presence of Zn powder and ultrasound gave CF3CH(OH)CH2CO2Et, which was dehydrated, then reduced (LiAlH4/AlCl3) to give CF3CH:CHCH2OH. Also prepared were RCH:CHCH(OH)CF3 (R = Bu, Ph), RCMe:CHCH(OH)CF3 (same R), CF3CH(OH)CHR1CH:CH2 (R1 = H, Me, Ph), and CF3CH(OH)CH2CCH.

Journal of Fluorine Chemistry published new progress about 83706-94-9. 83706-94-9 belongs to alcohols-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is (E)-4,4,4-Trifluorobut-2-en-1-ol, and the molecular formula is C4H5F3O, Application In Synthesis of 83706-94-9.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts