Gazizov, M. B.’s team published research in Russian Journal of General Chemistry in 85 | CAS: 6346-09-4

Russian Journal of General Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Synthetic Route of 6346-09-4.

Gazizov, M. B. published the artcile4-(Dibromomethyl)benzaldehyde and its reactions with primary amines, Synthetic Route of 6346-09-4, the publication is Russian Journal of General Chemistry (2015), 85(9), 2209-2211, database is CAplus.

The title compound, 4-Br2CHC6H4CHO (1) was prepared by reaction of 1,4-(Br2CH)2C6H4 with tri-Me phosphate with 42% yield, the side product being di-Me phosphorobromidate (MeO)2P(O)Br. The process shows advantages over usual acid hydrolysis, being selective and leaving less aggressive hydrogen bromide waste. The aldehyde 1 reacts with primary amines RNH2, giving aldimines 4-Br2CHC6H4CH:NR [13a–d; R = iPr, 4-MeOC6H4, CH2CH(OEt)2, (CH2)3CH(OEt)2].

Russian Journal of General Chemistry published new progress about 6346-09-4. 6346-09-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Ether, name is 4,4-Diethoxybutan-1-amine, and the molecular formula is C8H19NO2, Synthetic Route of 6346-09-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts