Tetrahedron Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Name: (R)-Oxiran-2-ylmethanol.
Gajare, Vikas S. published the artcileDiversity oriented concise asymmetric synthesis of azasugars: a facile access to L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine, Name: (R)-Oxiran-2-ylmethanol, the publication is Tetrahedron Letters (2015), 56(48), 6659-6663, database is CAplus.
Diversity oriented concise asym. syntheses of L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine have been developed from (R)-glycidol. The key step of the synthesis is Sharpless asym. dihydroxylation on enantiomerically pure TBDMS protected allylic alc. I which generates the triol intermediate II in excellent de. The (2R,3R,4S)-2,3-dihydroxypentanoate derivative II was subsequently converted to natural pyrrolidine azasugar L-2,3-trans-3,4-cis-dihydroxyproline and non-natural piperidine azasugar III under cascade reaction conditions in good yields.
Tetrahedron Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Name: (R)-Oxiran-2-ylmethanol.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts