Filimonova, A. V. published the artcile3D-modeling of the influence of isomalt, glucose, and compaction pressure on the quality of ascorbic-acid tablets, SDS of cas: 64519-82-0, the main research area is isomalt glucose compaction modeling ascorbic acid tablet.
The influence of the isomalt mass fraction in a mixture with glucose on the flowability, d., and elastic-plastic properties of the tableting mass and the quality of the obtained 1-g tablets (14 mm diameter) was studied. The flowability of the mixture decreased by 0.6 ± 0.06 g/c if the isomalt ST-PF content was increased by 10%. The curve for the bulk d. had a distinct maximum near an isomalt-glucose ratio of 50:50. The tablet strength increased linearly by 55 ± 7 and 51 ± 7 N; the d., by 0.0036 ± 0.0002 and 0.076 ± 0.003 g/cm3; and the disintegration time, by 1.2 ± 0.2 and 1.7 ± 02 min if the isomalt ST-PF concentration in the mixture was increased to 35% and the compaction pressure to 350 N/cm2, resp.
Pharmaceutical Chemistry Journal published new progress about Compaction. 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, SDS of cas: 64519-82-0.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts