Chen, Yuming’s team published research in European Journal of Organic Chemistry in 2021 | CAS: 4410-99-5

European Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Computed Properties of 4410-99-5.

Chen, Yuming published the artcileTwo-step protocol for iodotrimethylsilane-mediated deoxy-functionalization of alcs., Computed Properties of 4410-99-5, the publication is European Journal of Organic Chemistry (2021), 2021(7), 1179-1183, database is CAplus.

We have developed a two-step protocol for iodotrimethylsilane-mediated deoxy-functionalization of primary and secondary alcs. to afford products containing a C-N, C-S, or C-O bond. In the first step the alc. undergoes iodination with iodotrimethylsilane, and in the second, the iodine atom is replaced by a N, S, or O nucleophile. Compared with traditional Mitsunobu reaction, non-acidic pre-nucleophiles can be used, and the reaction proceeds with retention of configuration. This operationally simple, highly efficient protocol can be used for some natural products and small-mol. drugs containing hydroxy-group.

European Journal of Organic Chemistry published new progress about 4410-99-5. 4410-99-5 belongs to alcohols-buliding-blocks, auxiliary class Thiol,Benzene, name is 2-Phenylethanethiol, and the molecular formula is C8H10S, Computed Properties of 4410-99-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts