Borkowski, Olivier published the artcileLarge scale active-learning-guided exploration for in vitro protein production optimization, Computed Properties of 122-20-3, the publication is Nature Communications (2020), 11(1), 1872, database is CAplus and MEDLINE.
Abstract: Lysate-based cell-free systems have become a major platform to study gene expression but batch-to-batch variation makes protein production difficult to predict. Here we describe an active learning approach to explore a combinatorial space of ~4,000,000 cell-free buffer compositions, maximizing protein production and identifying critical parameters involved in cell-free productivity. We also provide a one-step-method to achieve high quality predictions for protein production using minimal exptl. effort regardless of the lysate quality.
Nature Communications published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C9H21NO3, Computed Properties of 122-20-3.
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