Wang, Xuerong published the artcileTransition Metal-Free Aerobic Oxidation of Aryl Secondary and Primary Alcohols to Carbonyl Compounds in Open Air, Synthetic Route of 90-64-2, the publication is ChemistrySelect (2022), 7(3), e202103502, database is CAplus.
Here, an efficient and practical oxidation of aryl secondary and primary alcs. R1CH(OH)R2 (R1 = Ph, biphenyl-4-yl, 2-naphthyl, etc., R2 = H, ME, Et, CO2H, 4-ClC6H4, etc.) to the corresponding carbonyl compounds using NaOtBu in open air at room temperature has been developed. By utilizing NaOtBu/air/toluene, a series of ketones R1C(O)R2 or benzoic acids were obtained in high yields, resp. More importantly, most of the substrates with electron-withdrawing or electron-donating groups could be converted to the corresponding products in high to excellent yields. Furthermore, the practicality of the reaction was demonstrated through a 1.0 g-scale reaction with excellent yield.
ChemistrySelect published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C24H29N5O3, Synthetic Route of 90-64-2.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts