Shivarkar, Anandkumar B. published the artcileTandem Synthesis of β-Amino Alcohols from Aniline, Dialkyl Carbonate, and Ethylene Glycol, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol, the publication is Industrial & Engineering Chemistry Research (2008), 47(8), 2484-2494, database is CAplus.
An efficient tandem route for selective synthesis of β-amino alcs. from anilines, dialkyl carbonate and ethylene glycol in the presence of recyclable Na-Y zeolite was demonstrated. Transesterification of dialkyl carbonate by ethylene glycol produce ethylene carbonate which further reacts with aniline to give β-amino alcs. in a single step. This reaction system was studied under high-pressure and pot reaction condition. Various process parametric effects were studied for the reaction of aniline, dialkyl carbonate, and ethylene glycol. A maximum 51% yield of mono-β-amino alc., i.e., N-phenylethanolamine (NPEA). Is obtained under pressure conditions. The yield of NPEA was improved drastically (>91%) by carrying out the reaction under pot conditions using di-Et carbonate as transesterification agent. Finally activity and selectivity of solid catalyst was explained on the basis of nature of active sites and pore structure of the catalyst.
Industrial & Engineering Chemistry Research published new progress about 101-98-4. 101-98-4 belongs to alcohols-buliding-blocks, auxiliary class Amine,Benzene,Alcohol, name is 2-(Benzyl(methyl)amino)ethanol, and the molecular formula is C8H9BFNO3, Recommanded Product: 2-(Benzyl(methyl)amino)ethanol.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts