Salama, Paul published the artcileThe use of catalytic amounts of selected cationic surfactants in the design of new synergistic preservative solutions, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Cosmetics (2021), 8(2), 54, database is CAplus.
Preservation using combinations of antibacterial mols. has several advantages, such as reducing the level of usage and broadening their antimicrobial spectrum. More specifically, the use of quaternary ammonium surfactants (QAS)-which are profusely used in hair care products and some are known as efficient antimicrobial agents-is limited due to some potential cytotoxicity concerns. This study shows that the concentration of some widely used cosmetic preservatives can be decreased when combined with very small quantities of QAS, i.e., Polyquaternium-80 (P-80) and/or Didecyldimethylammonium chloride (DDAC). The antimicrobial activity of their mixtures was first evaluated by determining the min. inhibitory concentration (MIC) before and after the addition of QAS. Following up on this finding and targeting an ultimate consumer friendly antimicrobial blend, yet with optimal safety, we chose to utilize the food-grade preservative Maltol as the main natural origin antimicrobial agent mixed with min. concentrations of QAS to improve its moderate antimicrobial properties. The preservatives were tested for MIC values, challenge tests and synergy using the fractional inhibitory concentration index (FICI). The antimicrobial efficacy of Maltol was found to be synergistically improved by introducing catalytic amounts of P-80 and/or DDAC.
Cosmetics published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.
Referemce:
https://en.wikipedia.org/wiki/Alcohol,
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