Ryczaj, Klaudia’s team published research in Journal of Allergy and Clinical Immunology in 148 | CAS: 70445-33-9

Journal of Allergy and Clinical Immunology published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, COA of Formula: C11H24O3.

Ryczaj, Klaudia published the artcilePotentially harmful substances in moisturizers, COA of Formula: C11H24O3, the publication is Journal of Allergy and Clinical Immunology (2021), 148(2), 653-654, database is CAplus and MEDLINE.

A review. Despite the promising results of preliminary studies and hope for preventing atopic dermatitis (AD) and food allergy (FA) in high-risk infants by emollient application from their first days of life, further analyses failed to confirm the validity of such an approach. Haptens are low-mol.-weight chems. that may cause irritant or allergic contact dermatitis or subclin. skin barrier function changes. In 13 of the 17 emollients, at least 1 hapten was identified. The haptens found in the preparations were as follows: lanolin, iso-Pr myristate, phenoxyethanol, benzyl alc., sorbitan oleate, sorbitan sesquioleate, tocopheryl acetate, tocopherol, sorbic acid, propylene glycol, panthenol, ethylhexyl glycerin, cetearyl alc., cetyl alc., and stearyl alc. Thus, it is possible that chronic use of moisturizers containing haptens may lead to a vicious cycle of inflammation and skin barrier disruption that requires repeated applications of products

Journal of Allergy and Clinical Immunology published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, COA of Formula: C11H24O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts